{"id":1080,"date":"2023-10-26T12:11:23","date_gmt":"2023-10-26T03:11:23","guid":{"rendered":"https:\/\/ayabe-clinic.jp\/blog\/?p=1080"},"modified":"2023-10-26T12:17:30","modified_gmt":"2023-10-26T03:17:30","slug":"col-39","status":"publish","type":"post","link":"https:\/\/ayabe-clinic.jp\/blog\/col-39\/","title":{"rendered":"\u30b8\u30e5\u3079\u30eb\u30c3\u30af\/Juvelook(PDLLA)\u3068\u306f"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image3.png\" alt=\"\" class=\"wp-image-1083\" width=\"683\" height=\"512\" srcset=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image3.png 683w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image3-300x225.png 300w\" sizes=\"(max-width: 683px) 100vw, 683px\" \/><\/figure><\/div>\n\n\n<p>\u672c\u8a18\u4e8b\u3067\u306f\u3001\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u3068\u306f\u4f55\u304b\uff1f\u3069\u306e\u3088\u3046\u306a\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u306e\u304b\uff1f\u3053\u308c\u307e\u3067\u306e\u6cbb\u7642\u3068\u3069\u306e\u3088\u3046\u306a\u70b9\u3067\u7570\u306a\u308b\u306e\u304b\uff1f\u3055\u3089\u306b\u3001\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306e\u9577\u6240\u3068\u6ce8\u610f\u4e8b\u9805\u306b\u3064\u3044\u3066\u3054\u8aac\u660e\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"margin_b_medium has-background\" style=\"background-color:#ebebeb;font-size:14px\">\u57f7\u7b46\u8005 <a href=\"https:\/\/ayabe-clinic.jp\/doctor\">\u7dbe\u90e8 \u8aa0<\/a><br>\u798f\u5ca1\u7f8e\u5bb9\u76ae\u819a\u79d1\u3042\u3084\u3079\u30af\u30ea\u30cb\u30c3\u30af\u9662\u9577\u3002\u65e5\u672c\u7f8e\u5bb9\u5916\u79d1\u5b66\u4f1a\u8a8d\u5b9a\u7f8e\u5bb9\u5916\u79d1\u5c02\u9580\u533b\u3002\u6771\u4eac\u533b\u79d1\u5927\u5b66\u533b\u5b66\u90e8\u3092\u5352\u696d\u5f8c\u3001\u4e45\u7559\u7c73\u5927\u5b66\u75c5\u9662\u306e\u5f62\u6210\u5916\u79d1\u533b\u5e2b\u3068\u3057\u3066\u52e4\u52d9\u30021997\u5e74\u306b\u798f\u5ca1\u7f8e\u5bb9\u76ae\u819a\u79d1\u3042\u3084\u3079\u30af\u30ea\u30cb\u30c3\u30af\u958b\u9662\u3002\u7f8e\u5bb9\u5916\u79d1\u533b\u3068\u3057\u306630\u5e74\u4ee5\u4e0a\u306b\u308f\u305f\u308a\u52e4\u52d9\u3057\u305f\u7d4c\u9a13\u3092\u6d3b\u304b\u3057\u3001\u60c5\u5831\u767a\u4fe1\u3092\u884c\u3063\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306f\u30017.5 mg \u306e<strong>\u975e\u67b6\u6a4b\u30d2\u30a2\u30eb\u30ed\u30f3\u9178 (HA) \u306e\u6c34\u5206\u88dc\u7d66\u52b9\u679c<\/strong><sup>\u203b1<\/sup>\u306b\u3088\u308b\u5373\u6642\u5145\u586b\u52b9\u679c\u3068 \u6fc3\u5ea6 42.5 mg\u306ePDLLA (\u30dd\u30ea D,L-\u4e73\u9178) \u306b\u3088\u308b\u30b3\u30e9\u30fc\u30b2\u30f3\u751f\u6210\u306e\u9577\u671f\u523a\u6fc0\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u4e8c\u91cd\u52b9\u679c\u3092\u63d0\u4f9b\u3059\u308b\u6b21\u4e16\u4ee3\u306e\u6642\u9593\u6d3b\u6027\u578b\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9 \u30d5\u30a3\u30e9\u30fc\u3067\u3059\u3002\u3055\u3089\u306b\u3001\u3053\u306e\u88fd\u54c1\u306f\u3001 \u30a2\u30e1\u30ea\u30ab\u306e\u539a\u751f\u52b4\u50cd\u7701\u306b\u3042\u305f\u308b<strong>FDA \u306b\u3088\u3063\u3066\u5b89\u5168\u6027\u304c\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059<\/strong><sup>\u203b2<\/sup>\u3002<\/p>\n\n\n\n<p>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306f\u3001\u6ce8\u5165\u76f4\u5f8c\u306e\u52b9\u679c\u3070\u304b\u308a\u3067\u306f\u306a\u304f\u3001\u6642\u9593\u3092\u304b\u3051\u3066\u81ea\u5206\u81ea\u8eab\u306e\u7dda\u7dad\u82bd\u7d30\u80de\u3092\u82e5\u8fd4\u3089\u305b\u3001\u82e5\u8fd4\u3063\u305f\u7dda\u7dad\u82bd\u7d30\u80de\u304b\u3089\u30b3\u30e9\u30fc\u30b2\u30f3\u751f\u6210\u3092\u4fc3\u3057\u3066\u3044\u304f\u305f\u3081\u3001\u6700\u5927\u52b9\u679c\u3092\u5b9f\u611f\u3059\u308b\u307e\u3067\u306b\u306f2\u301c3\u30f6\u6708\u7a0b\u5ea6\u304b\u304b\u308a\u307e\u3059\u3002<br>\u3057\u304b\u3057\u3001\u4e00\u5ea6\u751f\u6210\u3055\u308c\u305f\u30b3\u30e9\u30fc\u30b2\u30f3\u306f\u3001\u6ce8\u5165\u3055\u308c\u305f\u30b3\u30e9\u30fc\u30b2\u30f3\u3067\u306f\u306a\u304f\u3001\u81ea\u5206\u81ea\u8eab\u306e\u7d30\u80de\u304c\u65b0\u305f\u306b\u65b0\u751f\u3057\u305f\u30b3\u30e9\u30fc\u30b2\u30f3\u3067\u3042\u308b\u305f\u3081\u5206\u89e3\u3055\u308c\u305a\u6b8b\u5b58\u3059\u308b\u306e\u3067\u3001\u6301\u7d9a\u7684\u306a\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p class=\"margin_b_none\">\u203b1 \u975e\u67b6\u6a4b\u30d2\u30a2\u30eb\u30ed\u30f3\u9178 (HA) \u306e\u6c34\u5206\u88dc\u7d66\u52b9\u679c\n<\/p><cite>\u51fa\u5178\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10005802\/\" target=\"_blank\" rel=\"noreferrer noopener\">The Effects of a Non-crossed-linked Hyaluronic Acid Gel on the Aging Signs of the Face versus Normal Saline: A Randomized, Double-blind, Placebo-controlled, Split-faced Study<\/a><\/cite><\/blockquote>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p class=\"margin_b_none\">\u203b2 FDA \u306b\u3088\u3063\u3066\u5b89\u5168\u6027\u304c\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059<\/p><cite>\u51fa\u5178\uff1a<a href=\"https:\/\/www.fda.gov\/medical-devices\/aesthetic-cosmetic-devices\/fda-approved-dermal-fillers\" target=\"_blank\" rel=\"noreferrer noopener\">FDA-Approved Dermal Fillers<\/a><\/cite><\/blockquote>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"821\" src=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image8-1024x821.png\" alt=\"\" class=\"wp-image-1088\" srcset=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image8-1024x821.png 1024w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image8-300x241.png 300w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image8-768x616.png 768w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image8.png 1147w\" sizes=\"(max-width: 767px) 89vw, (max-width: 1000px) 54vw, (max-width: 1071px) 543px, 580px\" \/><figcaption><strong>\u203b\u30b8\u30e5\u3079\u30eb\u30c3\u30af\u306e\u30d1\u30c3\u30b1\u30fc\u30b8<\/strong><\/figcaption><\/figure><\/div>\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6b21\u4e16\u4ee3\u578b\u30d5\u30a3\u30e9\u30fc\u3068\u306f\uff1f<\/strong><\/h3>\n\n\n\n<p>\u300c\u6b21\u4e16\u4ee3\u578b\u300d\u3068\u3044\u3046\u610f\u5473\u306b\u306f\u4e8c\u3064\u306e\u610f\u5473\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u3064\u76ee\u306f\u3001\u4eca\u307e\u3067\u306e\u30d5\u30a3\u30e9\u30fc\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u306a\u3089\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u307f\u3001\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u306a\u3089\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u306e\u307f\u306e\u5358\u4f53\u306e\u7d20\u6750\u3067\u51fa\u6765\u3066\u3044\u305f\u6210\u5206\u3067\u3059\u304c\u3001\u4eca\u56de\u306e\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306f\u3001\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u3068PDLLA\uff08\u30dd\u30ea D,L-\u4e73\u9178\uff09\u306e\u4e8c\u3064\u306e\u6210\u5206\u3067\u51fa\u6765\u3066\u3044\u308b\u3053\u3068\u3002\u4e8c\u3064\u76ee\u306f\u3001\u4eca\u307e\u3067\u306e\u30d5\u30a3\u30e9\u30fc\u306f\u7d30\u80de\u3092\u82e5\u8fd4\u3089\u305b\u308b\u4e8b\u3067\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u65b0\u751f\u3059\u308b\u3053\u3068\u306f\u51fa\u6765\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u3001PDLLA\u88fd\u5264\u3067\u3042\u308b\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306f\u3001\u7d30\u80de\uff08\u3053\u306e\u5834\u5408\u306f\u7dda\u7dad\u82bd\u7d30\u80de\uff09\u3092\u82e5\u8fd4\u3089\u305b\u308b\u4e8b\u306b\u3088\u3063\u3066\u81ea\u5206\u3067\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u65b0\u305f\u306b\u751f\u6210\u3055\u305b\u308b\u3053\u3068\u304c\u51fa\u6765\u308b\u70b9\u304c\u300c\u6b21\u4e16\u4ee3\u578b\u306e\u30d5\u30a3\u30e9\u30fc\u300d\u305f\u308b\u7406\u7531\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7dda\u7dad\u82bd\u7d30\u80de\u306f\u3001\u52a0\u9f62\u3068\u3068\u3082\u306b\u6d3b\u6027\u304c\u4f4e\u4e0b\u3057\u30b3\u30e9\u30fc\u30b2\u30f3\u3068\u30a8\u30e9\u30b9\u30c1\u30f3\u7523\u6027\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u6765\u307e\u3059\u3002<strong>PDLLA\u88fd\u5264\u306f\u3001\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u6d3b\u6027\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u3067\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3068\u30a8\u30e9\u30b9\u30c1\u30f3\u306e\u7523\u751f\u3092\u4fc3\u9032\u3057\u3001\u808c\u306e\u30cf\u30ea\u3084\u5f3e\u529b\u3092\u6539\u5584\u3057\u307e\u3059<\/strong><sup>\u203b3<\/sup>\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p class=\"margin_b_none\">\u203b3 PDLLA\u88fd\u5264\u306f\u3001\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u6d3b\u6027\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u3067\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3068\u30a8\u30e9\u30b9\u30c1\u30f3\u306e\u7523\u751f\u3092\u4fc3\u9032\u3057\u3001\u808c\u306e\u30cf\u30ea\u3084\u5f3e\u529b\u3092\u6539\u5584\u3057\u307e\u3059<\/p><cite>\u51fa\u5178\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10294940\/\" target=\"_blank\" rel=\"noreferrer noopener\">Poly-D,L-Lactic Acid Filler Increases Extracellular Matrix by Modulating Macrophages and Adipose-Derived Stem Cells in Aged Animal Skin\n<\/a><\/cite><\/blockquote>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306e\u97d3\u56fd\u3067\u306e\u8a55\u4fa1<\/strong><\/h3>\n\n\n\n<p>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306f\u3001\u97d3\u56fd\u306b\u304a\u3044\u3066\u6d88\u8cbb\u8005\u306e\u5168\u9762\u7684\u306a\u652f\u6301\u3092\u53d7\u3051\u30012021\u5e74\u30682022\u5e74\u306e2\u5e74\u9023\u7d9a\u3067<strong>\u30b9\u30ad\u30f3\u30d6\u30fc\u30b9\u30bf\u30fc\u90e8\u9580\u3067\u300c\u97d3\u56fd\u306e\u6d88\u8cbb\u8005\u5927\u8cde\u300d\u3092\u53d7\u8cde\u3057\u307e\u3057\u305f<\/strong><sup>\u203b4<\/sup>\u3002<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p class=\"margin_b_none\">\u203b4 \u30b9\u30ad\u30f3\u30d6\u30fc\u30b9\u30bf\u30fc\u90e8\u9580\u3067\u300c\u97d3\u56fd\u306e\u6d88\u8cbb\u8005\u5927\u8cde\u300d\u3092\u53d7\u8cde\u3057\u307e\u3057\u305f<\/p><cite>\u51fa\u5178\uff1a<a href=\"https:\/\/www.donga.com\/news\/article\/all\/20230627\/119962940\/1\" target=\"_blank\" rel=\"noreferrer noopener\">2023 \ud55c\uad6d\uc758 \uc18c\ube44\uc790\ub300\uc0c1]\uc2a4\ud0a8\ubd80\uc2a4\ud130 \ubd80\ubb38 \/ 2\ub144 \uc5f0\uc18dJUVE LOOK<br>\n( \u97d3\u56fd\u306e\u65b0\u805e\u793e\u3067\u3042\u308b\u6771\u4e9c\u65e5\u5831\u306e\u65b0\u805e\u8a18\u4e8b\u3067\u3059\u3002)\n<\/a><\/cite><\/blockquote>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image2-1-1024x1024.png\" alt=\"\" class=\"wp-image-1082\" srcset=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image2-1-1024x1024.png 1024w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image2-1-300x300.png 300w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image2-1-150x150.png 150w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image2-1-768x768.png 768w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image2-1-100x100.png 100w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image2-1.png 1080w\" sizes=\"(max-width: 767px) 89vw, (max-width: 1000px) 54vw, (max-width: 1071px) 543px, 580px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306e\u4e3b\u306a\u52b9\u679c<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\"><li>\u808c\u306e\u30cf\u30ea\u3084\u5f3e\u529b\u30a2\u30c3\u30d7<\/li><li>\u30cb\u30ad\u30d3\u8de1\u3084\u30af\u30ec\u30fc\u30bf\u30fc\u306e\u6539\u5584<\/li><li>\u30b7\u30ef\u3084\u5c0f\u30b8\u30ef\u306e\u6539\u5584<\/li><li>\u6bdb\u7a74\u306e\u958b\u304d\u306e\u6539\u5584<\/li><li>\u598a\u5a20\u7dda\u306e\u6539\u5584<\/li><li>\u50b7\u306e\u8d64\u307f\u306e\u6539\u5584<\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306e\u9577\u6240<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\"><li>\u6301\u7d9a\u7684\u306a\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u3002<\/li><li>\u808c\u306e\u30cf\u30ea\u3084\u5f3e\u529b\u30a2\u30c3\u30d7\u3001\u30cb\u30ad\u30d3\u8de1\u3084\u30af\u30ec\u30fc\u30bf\u30fc\u3001\u30b7\u30ef\u3084\u5c0f\u30b8\u30ef\u3001\u6bdb\u7a74\u306e\u958b\u304d\u306e\u6539\u5584\u306a\u3069\u3001\u5e45\u5e83\u3044\u808c\u60a9\u307f\u306b\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u304d\u308b\u3002<\/li><li>\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u6ce8\u5165\u306e\u3088\u3046\u306b\u3001\u6ce8\u5165\u76f4\u5f8c\u306b\u52b9\u679c\u304c\u51fa\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u305f\u3081\u3001\u30c0\u30a6\u30f3\u30bf\u30a4\u30e0\u304c\u5c11\u306a\u3044\u3002<\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306e\u6ce8\u610f\u4e8b\u9805<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\"><li>\u6ce8\u5165\u76f4\u5f8c\u3001\u8d64\u307f\u3001\u816b\u308c\u3001\u75db\u307f\u3001\u8d64\u307f\u306a\u3069\u304c\u51fa\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u4e00\u6642\u7684\u306a\u3082\u306e\u3067\u6570\u65e5\u3067\u8efd\u6e1b\u3055\u308c\u307e\u3059\u3002<\/li><li>\u6ce8\u5c04\u5f8c3\u301c7\u65e5\u9593\u306f\u3001\u904e\u5ea6\u306e\u98f2\u9152\u3001\u30b5\u30a6\u30ca\u3001\u71b1\u3044\u98a8\u5442\u3001\u6fc0\u3057\u3044\u904b\u52d5\u3092\u907f\u3051\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/li><li>\u808c\u304c\u4e7e\u71e5\u3057\u306a\u3044\u3088\u3046\u306b\u4fdd\u6e7f\u5264\u3084\u518d\u751f\u30af\u30ea\u30fc\u30e0\u3092\u983b\u7e41\u306b\u4f7f\u7528\u3057\u3001\u5916\u51fa\u6642\u306b\u306f\u65e5\u713c\u3051\u6b62\u3081\u3092\u5857\u308b\u3053\u3068\u3092\u5e38\u306b\u304a\u52e7\u3081\u3057\u307e\u3059\u3002<\/li><li>\u307e\u308c\u306b\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u671b\u307e\u3057\u304f\u306a\u3044\u7d50\u679c\u3068\u3057\u3066\u306f\u3001\u6ce8\u5c04\u90e8\u4f4d\u306e\u708e\u75c7\u3001\u611f\u67d3\u3001\u8089\u82bd\u816b\u306e\u6669\u767a\u767a\u751f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3001\u8541\u9ebb\u75b9\u3001\u6ce8\u5c04\u90e8\u4f4d\u306e\u76ae\u819a\u80a5\u5927\u304a\u3088\u3073\u840e\u7e2e\u3001\u8840\u7ba1\u6d6e\u816b\u3001\u6bdb\u7d30\u8840\u7ba1\u62e1\u5f35\u3001\u76ae\u819a\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u3001\u7622\u75d5\u5316\u3001\u76ae\u819a\u5909\u8272\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002<\/li><\/ul>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1000\" height=\"570\" src=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image6.png\" alt=\"\" class=\"wp-image-1086\" srcset=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image6.png 1000w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image6-300x171.png 300w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image6-768x438.png 768w\" sizes=\"(max-width: 767px) 89vw, (max-width: 1000px) 54vw, (max-width: 1071px) 543px, 580px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306e\u52b9\u679c\u3068\u6301\u7d9a\u671f\u9593<\/strong><\/h3>\n\n\n\n<p>\u975e\u67b6\u6a4b\u30d2\u30a2\u30eb\u30ed\u30f3\u9178 (HA) \u306e\u6c34\u5206\u88dc\u7d66\u52b9\u679c\u306f\u3001\u4f7f\u7528\u76f4\u5f8c\u304b\u3089\u3042\u308a\u307e\u3059\u3002\u4e3b\u4f5c\u7528\u3067\u3042\u308b\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u82e5\u8fd4\u308a\u52b9\u679c\u306b\u3088\u308b\u30b3\u30e9\u30fc\u30b2\u30f3\u3068\u30a8\u30e9\u30b9\u30c1\u30f3\u306e\u65b0\u751f\u306f2\u9031\u76ee\u304b\u3089\u767a\u73fe\u3055\u308c\u307e\u3059\u304c\u3001\u8089\u773c\u3067\u52b9\u679c\u304c\u5b9f\u611f\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u306b\u306f8\u9031\u9593\u5fc5\u8981\u3067\u3059\u3002\u6301\u7d9a\u52b9\u679c\u306f12\u301c18\u6708\u9593\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u63a8\u5968\u3059\u308b\u6cbb\u7642\u30b3\u30fc\u30b9<\/strong><\/h3>\n\n\n\n<p>\u808c\u306e\u72b6\u614b\u306b\u5fdc\u3058\u30666\u301c8\u9031\u6bce\u306b3\u56de\u6cbb\u7642\u3057\u3001\u305d\u306e\u5f8c6\u301c12\u6708\u3054\u3068\u306b1\u56de\u306e\u30e1\u30f3\u30c6\u30ca\u30f3\u30b9\u6cbb\u7642\u3067\u6301\u7d9a\u3059\u308b\u9577\u671f\u7684\u306a\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u52b9\u679c\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30de\u30c3\u30af\u30fc\u30e0\uff08PLLA)\u3068\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\uff08PDLLA\uff09\u306e\u9055\u3044<\/strong><\/h3>\n\n\n\n<p>PLLA\u3068\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\uff08PDLLA\uff09\u306f\u3001\u3069\u3061\u3089\u306b\u3057\u3066\u3082\u8eab\u4f53\u306b\u3068\u3063\u3066\u306f\u7570\u7269\u3067\u3042\u308b\u3053\u3068\u306f\u540c\u3058\u306a\u306e\u3067\u3001\u6025\u6027\u671f\u3068\u6162\u6027\u671f\u306e2\u3064\u306e\u4f5c\u7528\u6a5f\u5e8f\u306b\u3088\u3063\u3066\u5206\u89e3\u3055\u308c\u307e\u3059\u3002\u3068\u3082\u306b2\u9031\u9593\u3059\u308b\u3068\u6c34\u3068\u4e8c\u9178\u5316\u70ad\u7d20\u306b\u5206\u89e3\u3055\u308c\u306f\u3058\u3081\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3001\u30a8\u30e9\u30b9\u30c1\u30f3\u304c\u65b0\u751f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7c21\u5358\u306b\u8aac\u660e\u3059\u308b\u3068\u30de\u30c3\u30af\u2015\u30e0\u306f\u76ae\u819a\u306b\u5165\u308c\u305f\u5206\u3060\u3051\u30b3\u30e9\u30fc\u30b2\u30f3\u306b\u7f6e\u63db\u3055\u308c\u307e\u3059\u304c\u3001\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306e\u65b9\u306f\u305d\u308c\u3070\u304b\u308a\u3067\u306f\u306a\u304f\u3001<strong>\u7dda\u7dad\u82bd\u7d30\u80de\u305d\u306e\u3082\u306e\u3092\u5897\u6b96\u3057\u3001\u3055\u3089\u306b\u82e5\u8fd4\u3089\u305b\u308b<\/strong>\u3053\u3068\u304c\u51fa\u6765\u308b\u306e\u3067\u3001\u82e5\u8fd4\u3063\u305f\u7dda\u7dad\u82bd\u7d30\u80de\u304c\u3001\u3055\u3089\u306b\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u65b0\u751f\u3055\u305b\u308b\u3053\u3068\u304c\u51fa\u6765\u307e\u3059\u3002\u3064\u307e\u308a\u3001<strong>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306e\u65b9\u304c\u3088\u308a\u591a\u304f\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u65b0\u751f\u3067\u304d\u307e\u3059<\/strong>\u3002<\/p>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" data-id=\"1084\" src=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image4-1.png\" alt=\"\" class=\"wp-image-1084\" width=\"414\" height=\"490\" srcset=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image4-1.png 414w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image4-1-253x300.png 253w\" sizes=\"(max-width: 414px) 100vw, 414px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"483\" height=\"490\" data-id=\"1085\" src=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image5.png\" alt=\"\" class=\"wp-image-1085\" srcset=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image5.png 483w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image5-296x300.png 296w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image5-100x100.png 100w\" sizes=\"(max-width: 483px) 100vw, 483px\" \/><\/figure>\n<\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u306e\u4f5c\u7528\u6a5f\u5e8f<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u5206\u5b50\u751f\u7269\u5b66\u7684\u306b\u8001\u5316\u3068\u306f\u4f55\u304b\uff1f<\/strong><\/h4>\n\n\n\n<p>\u300c<strong>\u8001\u5316\u3068\u306f\u7d30\u80de\u5185\u3067\u751f\u3058\u308b\u9178\u5316\u3067\u3042\u308b<\/strong>\u300d<sup>\u203b5<\/sup>\u3068\u5b9a\u7fa9\u3059\u308b\u3053\u3068\u304c\u51fa\u6765\u307e\u3059\u3002<br>\u7d30\u80de\u3092\u4eba\u70ba\u7684\u306b\u8001\u5316\u3055\u305b\u308b\u65b9\u6cd5\u3068\u3057\u3066<strong>\u904e\u9178\u5316\u6c34\u7d20\uff08\u6614\u3001\u602a\u6211\u3057\u305f\u969b\u306b\u4f7f\u7528\u3057\u305f\u30aa\u30ad\u30b7\u30d5\u30eb\u3067\u3059\u306d\uff09\u3068\u3044\u3046\u300c\u9178\u300d\u306b\u6d78\u3059\u3053\u3068\u3067\u7d30\u80de\u3092\u9178\u5316\u3055\u305b\u3066\u3001\u8001\u5316\u3055\u305b\u308b<\/strong>\u3053\u3068\u304c\u51fa\u6765\u307e\u3059\u3002<br>\u3053\u308c\u306f\u3001\u5b9f\u969b\u306b\u306f\u4f53\u306e\u4e2d\u3067\u751f\u3058\u308b\u9178\u5316\u3059\u308b\u7269\u8cea\u3068\u305d\u308c\u3092\u53d6\u308a\u9664\u304f\u529b\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u308b\u3053\u3068\u3067\u8d77\u3053\u308a\u307e\u3059\u3002\u3053\u306e\u9178\u5316\u3059\u308b\u7269\u8cea\u304c\u5897\u3048\u308b\u3068\u3001\u76ae\u819a\u306e\u7d30\u80de\u304c\u30c0\u30e1\u30fc\u30b8\u3092\u53d7\u3051\u300c\u8001\u5316\u300d\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<br>\u7c21\u5358\u306b\u307e\u3068\u3081\u308b\u3068\u3001<strong>\u76ae\u819a\u306e\u8001\u5316\u306f\u300c\u9178\u5316\u3059\u308b\u7269\u8cea\u300d\u3068\u300c\u305d\u308c\u3092\u9632\u3050\u529b\u300d\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u308b\u3053\u3068\u3067\u8d77\u3053\u308a\u307e\u3059\u3002<\/strong>\u305d\u3057\u3066\u3001\u3053\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u308b\u3053\u3068\u3067\u3001\u76ae\u819a\u306e\u3057\u308f\u3084\u305f\u308b\u307f\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br>\u76ae\u819a\u306e\u4e2d\u306b\u306f\u30b3\u30e9\u30fc\u30b2\u30f3\u3084\u30a8\u30e9\u30b9\u30c1\u30f3\u306a\u3069\u306e\u300c\u7d50\u5408\u7d44\u7e54\u300d\u3068\u3044\u3046\u3082\u306e\u304c\u3042\u308a\u3001\u3053\u308c\u304c\u3057\u3063\u304b\u308a\u3057\u3066\u3044\u308b\u3068\u76ae\u819a\u306f\u30d4\u30f3\u3068\u5f35\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u9178\u5316\u3059\u308b\u7269\u8cea\u304c\u5897\u3048\u308b\u3068\u3001\u3053\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u3084\u30a8\u30e9\u30b9\u30c1\u30f3\u306a\u3069\u306e\u7d50\u5408\u7d44\u7e54\u304c\u58ca\u308c\u3084\u3059\u304f\u306a\u308a\u3001\u76ae\u819a\u306e\u3057\u308f\u3084\u305f\u308b\u307f\u306e\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"713\" src=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image7-1024x713.png\" alt=\"\" class=\"wp-image-1087\" srcset=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image7-1024x713.png 1024w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image7-300x209.png 300w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image7-768x535.png 768w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/image7.png 1266w\" sizes=\"(max-width: 767px) 89vw, (max-width: 1000px) 54vw, (max-width: 1071px) 543px, 580px\" \/><figcaption>\uff08\u7dda\u7dad\u82bd\u7d30\u80de\u304c\u30b3\u30e9\u30fc\u30b2\u30f3\u3068\u30a8\u30e9\u30b9\u30c1\u30f3\u3092\u7523\u751f\u3057\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u304c\u30d5\u30a7\u30f3\u30b9\u306e\u91dd\u91d1\u306e\u3088\u3046\u306b\u5f62\u3092\u4fdd\u3061\u3001\u30a8\u30e9\u30b9\u30c1\u30f3\u304c\u7d50\u675f\u30d0\u30f3\u30c9\u306e\u3088\u3046\u306b\u7de9\u307e\u306a\u3044\u3088\u3046\u30b3\u30e9\u30fc\u30b2\u30f3\u540c\u58eb\u3092\u7d50\u675f\u3057\u3066\u3044\u308b\uff09<\/figcaption><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p class=\"margin_b_none\">\u203b5 \u8001\u5316\u3068\u306f\u7d30\u80de\u5185\u3067\u751f\u3058\u308b\u9178\u5316\u3067\u3042\u308b<\/p><cite>\u51fa\u5178\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5927356\/\" target=\"_blank\" rel=\"noreferrer noopener\">Oxidative stress, aging, and diseases<\/a><\/cite><\/blockquote>\n\n\n\n<p>\u5177\u4f53\u7684\u306b\u8aac\u660e\u3057\u307e\u3059\u306d\u3002<\/p>\n\n\n\n<p>\u300c\u7a93\u306f\u4f55\u304b\u3089\u51fa\u6765\u3066\u3044\u307e\u3059\u304b\uff1f\u300d\u3068\u8cea\u554f\u3059\u308b\u3068\u666e\u901a\u300c\u30ac\u30e9\u30b9\u3067\u3057\u3087\uff01\uff1f\u300d\u3068\u7b54\u3048\u307e\u3059\u304c\u3001<br>\u3088\uff5e\uff5e\u304f\u8003\u3048\u3066\u307f\u308b\u3068\u300c\u30ac\u30e9\u30b9\u3068\u305d\u306e\u67a0\u7d44\u307f\u306e\u30b5\u30c3\u30b7\u304b\u3089\u306a\u3063\u3066\u3044\u307e\u3059\u300d\u3088\u306d\u3002<br>\u3053\u306e\u30b5\u30c3\u30b7\u306b\u5f53\u305f\u308b\u90e8\u5206\u304c\u7d50\u5408\u7d44\u7e54\u3067\u3042\u308b\u30b3\u30e9\u30fc\u30b2\u30f3\u3084\u30a8\u30e9\u30b9\u30c1\u30f3\u306a\u306e\u3067\u3059\u3002\u3053\u306e\u30b5\u30c3\u30b7\u3067\u3042\u308b\u30b3\u30e9\u30fc\u30b2\u30f3\u3084\u30a8\u30e9\u30b9\u30c1\u30f3\u304c\u58ca\u308c\u3066\u3001\u7de9\u3093\u3067\u6765\u308b\u304b\u3089\u30b7\u30ef\u3084\u305f\u308b\u307f\u304c\u751f\u3058\u3066\u304f\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u3053\u304b\u3089\u5b9f\u9a13\u3068\u305d\u306e\u8a3c\u660e\u306e\u8a71\u3057\u306a\u306e\u3067\u30c1\u30e7\u30c3\u30c8\u96e3\u3057\u304f\u306a\u308a\u307e\u3059\u3088\u3002<br>\u5b9f\u9a13\u3067\u3001<strong>\u30de\u30a6\u30b9\u7d30\u80de<\/strong>\u300cRAW264.7\u300d\u3068\u3044\u3046\u7d30\u80de\u3092\u904e\u9178\u5316\u6c34\u7d20\u306b\u6d78\u3059\u3053\u3068\u3067\u3001\u8001\u5316\u73fe\u8c61\u3092\u4eba\u70ba\u7684\u306b\u751f\u3058\u3055\u305b\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u305d\u306e\u5f8c\u306b\u4e09\u3064\u306e\u65b9\u6cd5\u3067\u51e6\u7406\u3057\u307e\u3059\u3002\u4e00\u3064\u306f\u751f\u7406\u98df\u5869\u6c34\u306b\u6d78\u3059\u3060\u3051\u306e\u5834\u5408\u3002\u4e8c\u3064\u76ee\u306f\u3001\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u3092\u542b\u3093\u3060\u751f\u7406\u98df\u5869\u6c34\u306b\u6d78\u3057\u305f\u5834\u5408\u3002\u4e09\u3064\u76ee\u306fPDLLA\u3092\u542b\u3093\u3060\u751f\u7406\u98df\u5869\u6c34\u306b\u6d78\u3057\u305f\u5834\u5408\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u6b21\u306bp21\u3068p16\u3068\u3044\u3046\u7269\u8cea\u306e\u91cf\u3092\u3001\u5404\u3005\u306e\u57f9\u5730\u306b\u3069\u306e\u304f\u3089\u3044\u306e\u91cf\u304c\u542b\u307e\u308c\u3066\u3044\u308b\u304b\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\u3053\u306e<strong>p21\u3068p16\u3068\u3044\u3046\u7269\u8cea\u306f\u3001\u5b9f\u306f\u8001\u5316\u3059\u308b\u3068\u91cf\u304c\u5897\u52a0<\/strong>\u3057\u3066\u304f\u308b\u7269\u8cea\u306a\u306e\u3067\u3059\u3002\u305d\u3046\u3059\u308b\u3068PDLLA\u3092\u542b\u3093\u3060\u751f\u7406\u98df\u5869\u6c34\u306b\u6d78\u3055\u308c\u305f\u7fa4\u304b\u3089\u691c\u51fa\u3055\u308c\u305fp21\u3068p16\u304c\u4e00\u756a\u5c11\u306a\u304b\u3063\u305f\u3053\u3068\u304c\u5224\u660e\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u6b21\u306e\u5b9f\u9a13\u3067\u306f\u3001\u4f53\u306e\u514d\u75ab\u6a5f\u80fd\u3092\u53f8\u308b<strong>\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8<\/strong>\u3068\u3044\u3046\u7d30\u80de\u306b\u7740\u76ee\u3057\u307e\u3057\u305f\u3002\u4f55\u6545\u306a\u3089\u3070PDLLA\u306f\u4f53\u306b\u3068\u3063\u3066\u306f\u300c\u7570\u7269\u300d\u3067\u3042\u308a\u3001\u3053\u308c\u3092\u8eab\u4f53\u306e\u4e2d\u306b\u6ce8\u5165\u3059\u308b\u308f\u3051\u3067\u3059\u304b\u3089\u3001\u3069\u306e\u69d8\u306a\u514d\u75ab\u53cd\u5fdc\u304c\u751f\u3058\u308b\u304b\u898b\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u3057\u3066\u3001\u5b9f\u306f\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306f2\u7a2e\u985e\u306b\u5206\u985e\u3059\u308b\u3053\u3068\u304c\u51fa\u6765\u307e\u3059\u3002\u4e00\u3064\u306fM1\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3068\u547c\u3070\u308c\u308b\u708e\u75c7\u3092\u751f\u3058\u308b\u7d30\u80de\u3068\u3001M2\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3068\u547c\u3070\u308c\u308b\u708e\u75c7\u5f8c\u306e\u4fee\u5fa9\u306b\u95a2\u4e0e\u3059\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u5206\u985e\u3067\u304d\u307e\u3059\u3002\u4eca\u56de\u306f\u3053\u306e<strong>\u4fee\u5fa9\u306b\u95a2\u4e0e\u3059\u308bM2\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u7d30\u80de<\/strong>\u3092\u4f7f\u7528\u3057\u3066\u5b9f\u9a13\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u524d\u56de\u540c\u69d8\u306b\u307e\u305a\u3001\u904e\u9178\u5316\u6c34\u7d20\u3092\u7528\u3044\u3066M2\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u7d30\u80de\u3092\u4eba\u70ba\u7684\u306b\u8001\u5316\u3055\u305b\u307e\u3057\u305f\u3002\u6b21\u306b\u524d\u56de\u306fp21\u3068p16\u3092\u8a08\u6e2c\u3059\u308b\u3053\u3068\u3067\u3001\u7d30\u80de\u304c\u3069\u308c\u3060\u3051\u8001\u5316\u3057\u305f\u304b\u3092\u8a08\u6e2c\u3057\u307e\u3057\u305f\u304c\u3001\u4eca\u56de\u306eM2\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3067\u306f\u3001\u7d30\u80de\u5185\u306b\u3042\u308b\u300cNRF2\u300d\u3068\u300cCD206\u300d\u3055\u3089\u306b\u5916\u90e8\u306b\u653e\u51fa\u3055\u308c\u308b\u300cIL-10\uff08\u30a4\u30f3\u30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class=\"wp-block-gallery aligncenter has-nested-images columns-default is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"240\" height=\"319\" data-id=\"1108\" src=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/52bffb014f2b12410dcb7aa9bd240247.jpg\" alt=\"\" class=\"wp-image-1108\" srcset=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/52bffb014f2b12410dcb7aa9bd240247.jpg 240w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/52bffb014f2b12410dcb7aa9bd240247-226x300.jpg 226w\" sizes=\"(max-width: 240px) 100vw, 240px\" \/><figcaption><strong>\u5de6\uff09\u5bfe\u7167<\/strong><\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"240\" height=\"319\" data-id=\"1106\" src=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/42000ee6bada7bd62d2d14b53d2a11e1.jpg\" alt=\"\" class=\"wp-image-1106\" srcset=\"https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/42000ee6bada7bd62d2d14b53d2a11e1.jpg 240w, https:\/\/ayabe-clinic.jp\/blog\/wp-content\/uploads\/2023\/10\/42000ee6bada7bd62d2d14b53d2a11e1-226x300.jpg 226w\" sizes=\"(max-width: 240px) 100vw, 240px\" \/><figcaption><strong>\u53f3\uff09\u30b8\u30e5\u30d9\u30eb\u30c3\u30af\u3092\u6ce8\u5165<\/strong><\/figcaption><\/figure>\n<figcaption 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